Hard cabin sterile isolator

TL-GZ-MISG8 Aseptic Production Isolator

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The advanced three-chamber design provides a continuously controllable dynamic Grade A clean environment, meeting the high standards required for sterile filling production
TL-GZ-MISG8无菌生产型隔离器
TL-GZ-MISG8 Aseptic Production Isolator | Product Details

Introduction

Innovative Three-Chamber Design

The TELING aseptic filling isolator adopts a three-chamber design, consisting of a transfer chamber, filling chamber, and crimping chamber, and is equipped with an integrated hydrogen peroxide generator to meet the requirements for simultaneous or separate sterilization of the three chambers.

High Customization and Automation

The TELING aseptic filling isolator can be fully customized according to the user's process requirements, implements modular assembly, and achieves automated production, greatly improving the efficiency of aseptic preparation production. It can also address contamination risks during the filling process of aseptic preparations and ATMP drugs.

Application Areas

Used for the isolation protection of key operations in the aseptic filling, stoppering, and crimping processes of preparations, to minimize the risk of external environmental pollution during filling operations, providing a smooth, standardized, and effective aseptic filling control process.

Product Features

Continuously Controllable Class A Clean Environment

Provides a continuously controllable dynamic Class A clean environment, ensuring the production environment remains controlled.

Fully Enclosed Physical Barrier

Provides a fully enclosed physical barrier, avoiding direct contact between operators and products, solving microbial contamination issues.

Real-time Environmental Monitoring

Can monitor settling bacteria, temperature, humidity, pressure, and wind speed in the environment in real-time, ensuring the production environment remains controlled.

Multi-functional Interface Configuration

All chambers of the isolator are pre-equipped with multi-functional interfaces, which can be configured with online floating bacteria and dust particle collection/detection equipment, and have in-situ sterilization capability.

Integrated Control and Compliance

Integrated control of the isolator and filling machine by an industrial computer, featuring multi-level login permission control, audit trail, and electronic signature functions, complying with FDA CFR21 PART11 regulations.

Full-process Data Traceability

The entire filling production process can be recorded, data is traceable, ensuring production compliance.

Automation and Intelligence

Automated and intelligent operation, reducing labor costs and improving production efficiency.

Advanced VHP Sterilization Technology

Integrates the latest generation Vaporized Hydrogen Peroxide (VHP) sterilizer developed by TELING with precise hydrogen peroxide gas concentration/saturation control technology, enabling rapid sterilization of the chamber environment.

Flexible Chamber Sterilization Options

Chambers can be sterilized together or each chamber can be sterilized separately, providing flexible production scheduling.

Cost Advantage: Using the TELING aseptic filling isolator can shorten project construction cycles and reduce operating costs; it can be placed in lower cleanliness environments (Class D), reducing operating costs; it can provide solutions for clean rooms with limited space.

Optional Configurations and Functions

Sterilization process compatibility testing and validation can be provided
Efficient VHP catalytic external decomposition device, achieving lower safe emission concentration
Efficient VHP catalytic internal decomposition device, capable of rapid decomposition to 1ppm
DPTE material transfer system
Aseptic liquid through-wall system
Integrated SCADA system (audit trail, electronic signature, PDF production batch report generation)
Video traceability system
Material scanning system
Paperless chart recorder

Compliance Standards

The TELING aseptic filling isolator fully complies with the following international standards and specifications:

FDA Standards
CFR21 Part 11
GMP Specifications
GAMP5 Guidelines

Design and Operational Advantages

Ergonomic Design

More ergonomic design, improving operational comfort and efficiency.

New Human-Machine Display Interface

Intuitive operation interface, simplifying operational procedures.

Front Top-Opening Window Design

Aseptic inflatable seal, equipped with safety lock, ensuring operational safety.

Integrated Glove Leak Testing System

Ensures the integrity and sealing of the isolator.

Easy Installation of Other Equipment

Facilitates the installation of other production equipment in the isolator, improving system compatibility.

Spacious Internal Operation Space

Provides ample operating space, improving work efficiency.

On-site Splice Assembly

Can be spliced and assembled on-site, facilitating installation and relocation.

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